morally? nothing, you are killing a non-living entity, therefor, no harm, no foul
however, a notice should be added to the start of the game (in very VERY small print) "DO NOT ATTEMPT TO RECREATE SCENES OR ACTIONS FOUND IN THIS GAME IN REAL LIFE I.E GO ON A KILLING SPREE, STEAL CARS etc etc..."
some people have a problem (mentally) where, they see it, therefor (to them) it is ok to do. these people are in a word.... stupid.
hope that helps
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